An in vivo neuroimmune organoid model to study human brain environment-dependent microglia phenotypes
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https://www.ncbi.nlm.nih.gov/sra/ERP146640
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资源简介：
Characterization of human stem cell-derived microglia (hMG) that develop within vascularized human brain organoids under physiological conditions in vivo. We isolated tdT+/CD45+ hMG from five animals and three time points (6, 12 and 24 weeks post transplantation) using Fluorescence-activated cell sorting (FACS), following a strictly controlled ex vivo isolation procedure as previously described (Gosselin et al., 2017) and profiled those cells using single cell RNA sequencing.
创建时间：
2023-10-13
