Quantitative analysis of the erythrocyte kinome

The erythrocytes, the most numerous cells of the human body (Sender 2016), have the fundamental function of providing oxygen to the other cells throughout the organism. Protein phosphorylations are involved in the regulation of several important mechanisms in erythrocytes, such as cytoskeleton remodeling and membrane deformability allowing them to transit into the smallest capillaries. We performed a label free quantitative analysis aimed at specifically identify the set of kinases expressed in erythrocytes (the erythrocyte kinome).