Total Synthesis of Clavilactone B: A Radical Cyclization–Fragmentation Strategy
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https://figshare.com/articles/dataset/Total_Synthesis_of_Clavilactone_B_A_Radical_Cyclization_Fragmentation_Strategy/2220151
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资源简介：
A new
synthetic route to clavilactone B, a naturally occurring inhibitor
of epidermal growth factor receptor (EGFR) tyrosine kinase, is disclosed.
The route features a sequential samarium-mediated radical cyclization–fragmentation
of an indanone derivative, which provides rapid access to a 10-membered
carbocyclic motif fused to an aromatic ring.
创建时间：
2016-02-16
