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Crystal structure of Aurora A in complex with VX-680 and TPX2

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Protein Data Bank Japan2024-10-30 更新2026-03-21 收录
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Crystal structure of Aurora A in complex with VX-680 and TPX2 Descriptor: CYCLOPROPANECARBOXYLIC ACID {4-[4-(4-METHYL-PIPERAZIN-1-YL)-6-(5-METHYL-2H-PYRAZOL-3-YLAMINO)-PYRIMIDIN-2-YLSULFANYL]-PHENYL}-AMIDE, SULFATE ION, Serine/threonine-protein kinase 6, ... Authors: Zhao, B, Smallwood, A, Lai, Z. Deposit date: 2008-08-13 Release date: 2008-10-28 Last modified: 2024-10-30 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Modulation of kinase-inhibitor interactions by auxiliary protein binding: crystallography studies on Aurora A interactions with VX-680 and with TPX2. Protein Sci., 17, 2008
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2008-08-13
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