Cryo-EM structure of CRBN-DDB1 in complex with HBS1L and TNG961
收藏Protein Data Bank Japan2026-05-06 更新2026-05-09 收录
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Cryo-EM structure of CRBN-DDB1 in complex with HBS1L and TNG961 Descriptor: DNA damage-binding protein 1, HBS1-like protein, N-{6-[(3R)-2,6-dioxopiperidin-3-yl]naphthalen-1-yl}-N'-{2-[6-(trifluoromethyl)-1-benzothiophen-2-yl]propan-2-yl}urea, ... Authors: Whittington, D.A. Deposit date: 2026-01-09 Release date: 2026-04-22 Last modified: 2026-05-06 Method: ELECTRON MICROSCOPY (2.9 Å) Cite: TNG961 is a selective oral HBS1L molecular glue degrader for the treatment of FOCAD-deleted cancers. Cancer Discov, 2026
创建时间：
2026-01-09
