The Cell Vision

TheCellVision.org is a freely available and web-accessible image visualization and data browsing tool that serves as a central repository for fluorescence microscopy images and associated quantitative data produced by high-content screening experiments. Currently, TheCellVision.org hosts images and associated analysis results from two published high- content screening (HCS) projects focused on the budding yeast Saccharomyces cerevisiae. TheCellVision.org allows users to access, visualize and explore fluorescence microscopy images, and to search, compare, and extract data related to subcellular compartment morphology, protein abundance, and localization. Each dataset can be queried independently or as part of a search across multiple datasets using the advanced search option. The website also hosts computational tools associated with the available datasets, which can be applied to other projects and cell systems, a feature we demonstrate using published images of mammalian cells. Providing access to HCS data through websites such as TheCellVision.org enables new discovery and independent re-analyses of imaging data."

TheCellVision.org 是一个免费且可通过网络访问的图像可视化及数据浏览工具，该工具作为荧光显微镜图像及其相关定量数据的中心存储库。目前，TheCellVision.org 收录了两个针对萌芽酵母 Saccharomyces cerevisiae 的已发表高内涵筛选（HCS）项目的图像及其相关分析结果。TheCellVision.org 允许用户访问、可视化并探索荧光显微镜图像，以及搜索、比较和提取与亚细胞室形态、蛋白质丰度和定位相关的数据。每个数据集均可独立查询，或作为通过高级搜索选项跨多个数据集的搜索的一部分。该网站还提供了与可用数据集相关的计算工具，这些工具可应用于其他项目和细胞系统，我们通过哺乳动物细胞的已发表图像展示了这一特性。通过 TheCellVision.org 等网站提供 HCS 数据的访问，有助于新发现的实现和成像数据的独立再分析。