Putative Looping Factor ZNF143/ZFP143 is an Essential Transcriptional Regulator with No Looping Function

Overview This repository contains all the raw fastSPT, FRAP, absolute abundance quantification data, and DESeq2 outputs associated with “Putative Looping Factor ZNF143/ZFP143 is an Essential Transcriptional Regulator with No Looping Function”. Cell lines, conditions, and experiments This repository has data for the following experiments, cell lines, and conditions. fastSPT tracks and FRAP quantification for: Histone H2B Halo-NLS CTCF C87 Clone D untreated Clone D ∆ZFP143 (2-4h) Clone A ZFP143 untreated Clone A ZFP143 ∆CTCF (2-4h) Clone B ZFP143 untreated Clone B ZFP143 ∆CTCF (2-4h) FRAP quantification for: Clone A CTCF untreated Clone A CTCF ∆ZFP143 (2-4h) Clone B CTCF untreated Clone B CTCF ∆ZFP143 (2-4h) WT mESC pDNN13 transfection WT mESC pDNN14 transfection WT mESC pDNN15 transfection DESeq2 outputs for: Clone A/B ∆ZFP143 vs untreated PRO-seq Clone A/B ∆CTCF vs untreated PRO-seq Clone A/B ∆ZFP143/∆CTCF vs untreated PRO-seq Clone D ∆ZFP143 vs untreated PRO-seq Other files: ZFP143 abundance quantification The parameters used for tracking (tracking_config.toml) The parameters used to get nuclear masks for fastSPT data (masking_params.csv)