C. Elegans Gene Expression

Genome data generated by BC Genome Sciences Centre is no longer available through this site as it is regularly deposited into controlled data repositories such as the European Genome Phenome Archive (EGA); ICGC (International Cancer Genome Consortium) and the Genome Data Commons (GDC) Using serial analysis of gene expression (SAGE) and microarrays, we are examining total mRNA populations in all developmental stages, both in whole worms and in specific cells and tissues. In addition, we are building promoter::GFP constructs to monitor gene expression in transgenic worms, focusing on C. elegans genes that have human orthologues. Also available are web-based PCR primer design tools, and access to information about our C. elegans Fosmid library.

由 BC 基因组科学中心生成的基因组数据，现已无法通过本站获取，因其定期存档于受控数据存储库，如欧洲基因组表型档案（EGA）、国际癌症基因组联盟（ICGC）以及基因组数据通用平台（GDC）。通过串联分析基因表达（SAGE）和微阵列技术，我们正在研究所有发育阶段中整体mRNA群体，包括完整虫体以及特定细胞和组织的mRNA。此外，我们正在构建启动子::GFP结构，以监控转基因虫的基因表达，重点关注具有人类同源基因的C. elegans基因。同时，我们还提供基于网络的PCR引物设计工具，以及访问我们C. elegans Fosmid库信息的权限。