Cryptococcus gattii is the causative agent of cryptococcosis infection that can lead to pneumonia and meningitis in immunocompetent individuals. The molecular basis of the pathogenic process and impac
The heart depends on a functional vasculature for oxygenation and transport of nutrients, and while occlusion of the coronary arteries can lead to myocardial infarction, it remains less explored how a
BackgroundThe prognosis of diffuse low-grade gliomas (DLGGs, WHO grade 2) is highly variable, making it difficult to evaluate individual patient outcomes. In this study, we used common clinical charac
Resistance to chemotherapy can occur through a wide variety of mechanisms. Resistance to tyrosine kinase inhibitors (TKIs) often arises from kinase mutationshowever, “off-target” resistance occurs bu
The role of somatic mitochondrial DNA (mtDNA) mutations in leukemogenesis remains poorlycharacterized. To determine the impact of somatic mtDNA mutations on the process, we assessed theleukemogenic po