The MLL – Menin interaction is a therapeutic vulnerability in NUP98-rearranged AML
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE232091
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资源简介：
To investigate the effect of Menin inhibitor on patient-derived NUP98-r AML. We treated primary AML cells with Menin inhibitor in a Mesenchymal stem cell co-Culture platform. Then we charachterized global gene expression in treated AML cells upon treatment in two different time points, day7 and day12. Comparative gene expression profiling analysis of RNA-seq data for patient-derived NUP98::NSD1 AML cells after treatment with Menin inhibitor (SNDX-5613/Revumenib).
创建时间：
2023-08-15
