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Crystal structure of Escherichia coli dihydrofolate reductase in complex with TRIMETHOPRIM

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Protein Data Bank Japan2023-10-18 更新2026-03-21 收录
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https://pdbj.org/mine/summary/7nae
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Crystal structure of Escherichia coli dihydrofolate reductase in complex with TRIMETHOPRIM Descriptor: Dihydrofolate reductase, SULFATE ION, TRIMETHOPRIM Authors: Estrada, A, Wright, D, Krucinska, J, Erlandsen, H. Deposit date: 2021-06-21 Release date: 2022-06-29 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.35 Å) Cite: Structure-guided functional studies of plasmid-encoded dihydrofolate reductases reveal a common mechanism of trimethoprim resistance in Gram-negative pathogens. Commun Biol, 5, 2022
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2021-06-21
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