AORTIC STENOSIS

The database includes 467 patients (mean age 80.6 ± 8.2 years; 51% men) with at least moderate aortic stenosis, and sinus rhythm. The primary study endpoint was the composite of all-cause mortality and hospitalizations for heart failure. The eligibility criteria were: 1. outpatient transthoracic echocardiogram performed between January 2019 and June 2022; 2. at least moderate AS by quantitively echocardiographic criteria(maximum aortic velocity ≥3 m/s or mean gradient≥30 mmHg or AVA ≤ 1.5 cm2). Exclusion criteria were moderate-to-severe mitral stenosis (MS), severe aortic regurgitation (AR), previous aortic valve surgery/transcatheter interventions, any established diagnosis of cardiomyopathy, missing relevant clinical data, and poor quality echocardiographic study unsuitable for a speckle tracking evaluation. Atrial fibrillation was also an exclusion criterion as it independently impact LA mechanics.