microRNA-637/661 ameliorate hypoxic induced pulmonary arterial hypertension by targeting TRIM29 signaling pathway

To investigate the synergistic effect of miR637/miR661 in PAH regulation, we overexpressed these two microRNAs in HPASMC cells cultured in a low oxygen environment.We then performed the RNA-seq assay to analysis gene expression profiles. Comparative gene expression profiling analysis of RNA-seq data for overexpressing miR637 and miR637 in HPASMC cultured in low oxygen environment.