Effect of GW2580 treatment on primary microglia transcriptome
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE185564
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The objective of this study was to assess transcriptomic changes to microglia as a result of treatment with the CSF1R angonist GW2580 in healthy mice. To determine how GW2580 affects microglia function, C57BL/6J mice were orally gavaged with vehicle or GW2580 (80mg/kg/d) for 8 days. Microglia were isolated by percoll gradient and then magnetically isolated with a CD11b+ positive selection kit to determine transcriptomic changes.
创建时间：
2021-12-15
