Decoder-seq enhances mRNA capture efficiency in spatial RNA sequencing

Decoder-seq offers exceptional flexibility and precision in spatial resolution with spot widths of 50, 25, and 15 um and various capture areas of spatially barcoded arrays. It was employed to mouse hippocampus, olfactory bulb and hemibrain, and human renal cancers.Decoder-seq 在空间分辨率方面具备卓越的灵活性与精确度，其空间条形码阵列（spatially barcoded arrays）的斑点宽度分别为50、25和15微米，且拥有多种捕获区域。该技术已被应用于小鼠海马体、嗅球、半脑以及人类肾癌。