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Immune Modulation of Platelet-Derived Mitochondria on memory CD4+ T Cells in humans

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NIAID Data Ecosystem2026-03-12 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP301458
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CD4-positive T cells are one of the key immune cells contributing to the immunopathogenesis of type 1 diabetes. Previous studies have reported that platelet-derived mitochondria suppress the proliferation of peripheral blood mononuclear cells (PBMC). To further characterize the immune modulation of platelet-derived mitochondria, the purified CD4-positive T cells were treated respectively with platelet-derived mitochondria. Current study demonstrated that platelet-derived mitochondria have a translational potential as novel immune modulators to treat T1D and other autoimmune diseases.
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2021-01-14
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