An Access to Aza-Freidinger Lactams and E‑Locked Analogs
收藏Figshare2016-02-20 更新2026-04-29 收录
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https://figshare.com/articles/dataset/An_Access_to_Aza_Freidinger_Lactams_and_i_E_i_Locked_Analogs/2447701
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Freidinger lactams, possessing a peptide bond configuration locked to Z, are important key elements of conformationally restricted peptidomimetics. In the present work, the CαHi+1 unit has been replaced by N, leading to novel aza-Freidinger lactams. A synthesis to corresponding building blocks and their E-locked analogs is introduced. The versatile buildings blocks reported here are expected to serve as useful elements in peptide synthesis.
创建时间:
2016-02-20



