Discovery of novel inhibitors of PDE10A
收藏Protein Data Bank Japan2023-09-06 更新2026-03-21 收录
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Discovery of novel inhibitors of PDE10A Descriptor: 2-{[4-(1-methyl-4-pyridin-4-yl-1H-pyrazol-3-yl)phenoxy]methyl}quinoline, MAGNESIUM ION, SULFATE ION, ... Authors: Pandit, J, Marr, E.S. Deposit date: 2009-06-08 Release date: 2009-08-04 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (1.53 Å) Cite: Discovery of a Novel Class of Phosphodiesterase 10A Inhibitors and Identification of Clinical Candidate 2-[4-(1-Methyl-4-pyridin-4-yl-1H-pyrazol-3-yl)-phenoxymethyl]-quinoline (PF-2545920) for the Treatment of Schizophrenia J.Med.Chem., 52, 2009
创建时间：
2009-06-08
