High-resolution mapping of homologous recombination events in rad3 hyper-recombination mutants

The Saccharomyces cerevisae RAD3 gene is homolog of human XPD, an essential gene encoding a DNA helicase of the TFIIH complex involved in both nucleotide excision repair (NER) and transcription酿酒酵母（Saccharomyces cerevisae）的RAD3基因是人类XPD的同源基因，而XPD作为一类必需基因，可编码TFIIH复合物的DNA解旋酶，参与核苷酸切除修复（nucleotide excision repair, NER）及转录过程。