Untreated and iron-treated ARPE-19 cell gene expression. Homo sapiens

To characterize the potential molecular pathway(s) affected by iron treatment and identify the one(s) responsible for C3 induction, we performed a whole genome microarray on untreated ARPE-19 cells and cells treated with 250 μM FAC for 48h/2d. Overall design: Gene expression was compared between untreated and FAC-treated ARPE-19 cells, with three biological replicates in each.