M2 mRNA is translated into protein M2-2
收藏reactome.org2025-01-15 收录
下载链接:
https://reactome.org/PathwayBrowser/#/R-HSA-9828714
下载链接
链接失效反馈官方服务:
资源简介:
Human respiratory syncytial virus (hRSV) M2 gene contains two overlapping open reading frames. Ribosomes translate the second ORF to the M2-2 protein after departing from the first ORF. This coupled translation depends on a coding region in the mRNA containing a high degree of secondary structure, directing the ribosome back onto the start codon of the second ORF (Ahmadian et al, 2000; Gould & Easton, 2005; Gould & Easton, 2007)
人类呼吸道合胞病毒(hRSV)M2基因包含两个相互重叠的开放阅读框。核糖体在离开第一个开放阅读框后,将第二个开放阅读框翻译成M2-2蛋白。这种偶联的翻译依赖于mRNA中的一个编码区域,该区域具有较高的二级结构,引导核糖体返回至第二个开放阅读框的起始密码子(Ahmadian 等人,2000年;Gould 与 Easton,2005年;Gould 与 Easton,2007年)
提供机构:
Reactome



