Developmental legacy of thymic agonist selection of Treg cells enforced by miR- 181a/b-1 determines their suppressive capacity

NIAID Data Ecosystem2026-05-26 收录

调节性T细胞功能

miRNA与免疫调控

数据链接：

https://www.ncbi.nlm.nih.gov/sra/SRP148988 数据链接链接失效反馈

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资源简介：

Analysis of the link between miR-181a/b-1 and Treg repertoire during T-cell development.

创建时间：

2019-02-11

Foxp3-dependent and -independent functions of peripherally-induced regulatory T cells: scRNA-seq. Foxp3-dependent and -independent functions of peripherally-induced regulatory T cells: scRNA-seq

调节性T细胞功能

单细胞RNA测序

Regulatory T (Treg) cells expressing the X-linked lineage-defining transcription factor (TF) Foxp3 are essential for preventing fatal autoimmunity. During thymic differentiation, Foxp3 expression is i

NIAID Data Ecosystem100

Global expression profiling of peripheral Qa-1 class Ib-restricted CD8aa+TCRab+ regulatory T Cells reveals innate-like features: implications for immune regulatory repertoire

细胞基因表达

调节性T细胞功能

To better understand the function of CD8aa Tregs, we have recently characterized several CD8aa+TCRab+ T cell clones and lines that are physiologically primed and are involved in recovery and protectio

NIAID Data Ecosystem50

Expression Data from regulatory T-cells in a model of acute pancreatitis. Expression Data from regulatory T-cells in a model of acute pancreatitis

调节性T细胞功能

急性胰腺炎机制

Foxp3 positive regulatory T-cells were isolated by FACS from spleen of mice with acute pancreatitis induced by partial pancreatic duct ligation, mice without pancreatitis refer as controls we used mic

NIAID Data Ecosystem30

Foxp3-dependent and -independent functions of peripherally-induced Treg cells [09748]

调节性T细胞功能

免疫耐受机制

Regulatory T (Treg) cells expressing the lineage-defining transcription factor Foxp3 are essential for the maintenance of immune tolerance. Foxp3 expression can be induced in a subset of developing se

NIAID Data Ecosystem60

Human Regulatory T Cell Suppressive Function Is Independent of Apoptosis Induction in Activated Effector T Cells

调节性T细胞功能

自身免疫疾病机制

BackgroundCD4+CD25+FOXP3+ Regulatory T cells (Treg) play a central role in the immune balance to prevent autoimmune disease. One outstanding question is how Tregs suppress effector immune responses in

NIAID Data Ecosystem40

Developmental legacy of thymic agonist selection of Treg cells enforced by miR- 181a/b-1 determines their suppressive capacity

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