Bullous pemphigoid (BP) is an autoimmune disorder characterized by tense blisters, urticarial plaques and intense pruritis. Initial treatment typically involves the use of topical and oral steroids; h
A hallmark of the gluten-driven enteropathy celiac disease is autoantibody production towards the enzyme transglutaminase 2 (TG2) that catalyzes the formation of covalent protein-protein cross-links.
Roles of all-trans-retinoic acid (tRA), a metabolite of vitamin A (VA), in both tolerogenic and immunogenic responses are documented. However, how tRA affects the development of systemic autoimmunity