Crystal structure of EGFR 696-1022 T790M in complex with LXX-6-26
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Crystal structure of EGFR 696-1022 T790M in complex with LXX-6-26 Descriptor: 1,2-ETHANEDIOL, 1-[(3R)-3-[4-azanyl-3-[3-chloranyl-4-[(6-methylpyridin-2-yl)methoxy]phenyl]pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]prop-2-en-1-one, Epidermal growth factor receptor Authors: Yan, X.E, Yun, C.H. Deposit date: 2016-08-23 Release date: 2017-09-06 Last modified: 2024-10-09 Method: X-RAY DIFFRACTION (3.14 Å) Cite: Discovery and characterization of a novel irreversible EGFR mutants selective and potent kinase inhibitor CHMFL-EGFR-26 with a distinct binding mode. Oncotarget, 8, 2017
创建时间：
2016-08-23
