A Phase III Prospective, Multi-center, Randomised, Evaluator-blinded Study to Compare Neuromuscular Junction (NMJ) Targeted Technique for Dysport Injections in Upper Limb Spasticity Post Stroke or Traumatic Brain Injury to the Technique Used in Current Clinical Practice

The aim of the study was to compare Dysport treatment results (as assessed by Modified
Ashworth Scale (MAS) in the elbow joint 4 weeks post treatment) following two treatment
techniques: the current clinical practice injection technique using high-concentration
dilution (300 U/mL Dysport) versus the neuromuscular junction (NMJ)-targeted injection
technique using low-concentration dilution (100 U/mL Dysport). The hypothesis was that one
high-volume, low-concentration injection located centrally in the area/band of the NMJ zones
would be as effective as the technique used in current medical practice.