Global H5N1 Mutation Burden: Ranked Trends in Genomic Sequences Span = Q1&2 2025 n=1205

This dataset provides ranked mutation burden analysis of H5N1 genomic sequences, highlighting variability across accessions. Visualized as line charts with trend lines, it supports research on viral evolution, immune escape, and genomic surveillance. Data includes mutation burden per sequence, mean burden, and rolling average trends for clarity.

H5N1 Mutation Burden Analysis Summary (2025)

=== Key Insights ===
- Total Sequences Analyzed: 1205
- Mean Mutation Burden: 1909.16
- Median Mutation Burden: 1918.00
- Range: 1728 (min) to 2190 (max)
- Top 10 Sequences by Mutation Burden:
Sequence_ID Mutation_Burden
gb|JF710592.1| 2190
gb|PQ724474.1| 2179
gb|PQ724474.1| 2160
gb|JF710593.1| 2156
gb|ON759335.1| 2145
lcl|consensus|GVAtlas 2136
lcl|consensus|GVAtlas 2133
gb|PQ724471.1| 2124
gb|JQ714219.1| 2123
gb|PQ816212.1| 2116

=== Sequence Counting ===
- Total Unique Sequences: 1001
- Sequences Above Mean Burden: 607
- Sequences Below Mean Burden: 598

=== Trend Analysis ===
- Most sequences cluster near the mean, with a few outliers showing significantly higher burdens.
- The rolling average trend line reveals a slight downward slope after top outliers.

=== Implications ===
- Outliers (e.g., `gb|JF710592.1|`, `gb|PQ724474.1|`) may indicate regions of active diversification or immune escape.
- The tight clustering around the mean suggests a stable mutation burden across most sequences.
Data processed and being curated by [e-mail]