ST36 acupoint alleviates cardiac fibrosis through A2AR-dependent regulation of microcirculation

Supplementary Table 1 included raw data corresponding to Figure 2 and 3, organized into four sheets. Sheet A: Percentage of cardiac fibrosis in Sham, ISO, ISO+ST36, ISO+PC6, and ISO+SA groups. Sheet B: Heart weight to body weight ratio (HW/BW). Sheet C: Echocardiographic parameters. Sheet D: Electrocardiogram (ECG) parameters across groups. Supplementary Table 2 contained raw data corresponding to Figure 4, with two sheets. Sheet A: Parameters from laser speckle contrast imaging in Sham, ISO, and ISO+ST36 groups. Sheet B: Hemodynamic variables. Supplementary Table 3 contained raw data corresponding to Figure 5, with four sheets. Sheet A: A2A receptor protein levels detected by immunohistochemistry in Sham, ISO, and ISO+ST36 groups. Sheet B: Gene expression of A2AR and A1R by qPCR. Sheet C: Serum cytokine levels measured by ELISA. Sheet D: Ventricular cytokine levels measured by ELISA. Supplementary Table 4 included raw data for Figure 6 and 7, organized into four sheets. Sheet A: Percentage of cardiac fibrosis in ISO, ISO+ST36, ISO+caffeine, and ISO+caffeine+ST36 groups. Sheet B: HW/BW. Sheet C: Echocardiographic parameters. Sheet D: ECG parameters. Supplementary Table 5 contained raw data related to Figure 8, with two sheets. Sheet A: Laser speckle contrast imaging parameters in ISO, ISO+ST36, ISO+caffeine, and ISO+caffeine+ST36 groups. Sheet B: Hemodynamic variables. Supplementary Table 6 included raw data supporting Figure 9, with four sheets. Sheet A: A2A protein levels by IHC in ISO, ISO+ST36, and ISO+caffeine+ST36 groups. Sheet B: PCR-based expression of A2AR and A1R. Sheet C: Serum cytokine levels by ELISA. Sheet D: Ventricular cytokine levels by ELISA.