SummaryThe GL261 syngeneic mouse model is the most widely used preclinical model for glioblastoma research, yet comprehensive spatial transcriptomic characterization of its tumor microenvironment is l
PTEN deficiency is known to lead to tumor-intrinsic resistance to immune checkpoint blockade (ICB) treatment, especially in glioblastoma (GBM). We used RNA sequence to study the global gene expression
SummaryThe GL261 syngeneic mouse model is the most widely used preclinical model for glioblastoma research, yet comprehensive spatial transcriptomic characterization of its tumor microenvironment is l