Transcriptome diversity and differential expression of supporting limb laminitis

To date, very few studies have examined laminitis from the transcriptome perspective. Our objective was to identify genes and pathways involved in the pathogenesis of equine supporting limb laminitis to further understanding of the disease etiology. We generated an updated lamellar transcriptome using PacBio Iso-Seq to supplement current equine annotation for differential expression analysis using Illumina RNA-seq.