Heart expression data from WT and reverb alpha KO mice after short ischemia/reperfusion at ZT0, ZT12

Nuclear receptor Reverb alpha is a component of circadian rythm which could be evolved in cardioprotection strategy. We test if pharmacological modulation of these target could be suitable for cardioprotection after ischemia reperfusion injury We used microarrays to detail the global programme of gene expression Heart ischemia reperfusion were performed using Langendorff isolated heart model and twenty minutes stop flow ishemia with twenty minutes reperfusion.