Database of Viral siRNA / shRNA

Viral siRNA Database (VIRsiRNAdb) is a structured collection of experimentally validated siRNAs reported in the scientific literature targeting diverse genes of important human viruses. The curation efforts to date has concentrated mainly on viruses known to be associated with infectious diseases in humans. Currently the database provides experimental information of 1358 siRNAs, mined from relevant Pubmed artcles, which includes siRNA sequence, virus subtype, target gene, GenBank accession, design algorithim, cell type, and efficacy.病毒小干扰RNA数据库（Viral siRNA Database，VIRsiRNAdb）是一套经过结构化整理的数据集，收录了已在科学文献中报道、经实验验证的小干扰RNA（small interfering RNA，siRNA），这些siRNA靶向多种重要人类病毒的不同基因。截至目前，该数据库的编目整理工作主要聚焦于已知与人类传染病相关的病毒。当前，该数据库共收录了从相关PubMed文献中挖掘得到的1358条siRNA的实验信息，涵盖siRNA序列、病毒亚型、靶基因、GenBank登录号、设计算法、细胞类型以及干扰效能。