Collection of putative promoter sequence of genes on different chromosomes of the human genome

Promoter serve as communication link between protein-based regulatory control systems and nucleotide-based sequence determinants that regulate gene expression. As such, promoters should be relatively well characterised as stretches of DNA sequence with transcription factor binding motifs should be candidates for promoter sequence for specific genes. But, the perennial problem of defining the start and end nucleotide of promoter remains unresolved, and promoter sequences for both prokaryotic and eukaryotic systems remain poorly defined. This work took the oft-used approach of estimating promoter sequence of genes by characterising 800 base pair sequence upstream of the gene start site as putative promoter sequence for all genes in the human genome. Using an in-house MATLAB genome analysis software, the start site and gene sequence of each gene in the human genome is determined, which provides foundational knowledge for estimating putative promoter sequence of each gene in the human genome. Defined in this way, putative promoter sequence should contain extraneous elements, but, these promoter sequences remain useful for initial characterisation of the functional basis of specific promoter of particular gene such as understanding the repertoire of transcription factors that bind to each promoter, as well as their qualitative binding affinity. The collection of promoter sequence of each gene in the human genome reported herein is catalogued based on each chromosome in the karyotype of humans, and may be useful for understanding possible chromosomal specificities in the sequence of promoters in the human genome.