Human Intestinal biopsy tissue LC-MS

This is the first report of proteomic analysis for the identification of novel drug targets based on intestinal biopsy tissue, which is significant to hypotheses for mechanistic investigation that are responsible for non-response to IFX and the development of clinical new pharmaceutical drugs. All 12 UC patients were divided into responders to IFX (UCinfG), non-responders to IFX (UCinfL), severe UC (UCsevere) without IFX treatment history and mild UC (UCmild) without IFX treatment history.