Additional file 9: of Motifome comparison between modern human, Neanderthal and Denisovan

List of human specific motifs for motif lengths 6–10 from core, proximal, distal promoters and introns as compared to Denisovan. Statistically significant motifs of lengths 6–10 from core, proximal, and distal promoters as well as introns unique to modern humans are listed (and not found in Denisovan). These motifs were found in the corresponding genomic subregion in modern human, and the number of such human-unique motifs were listed for each gene variant. From these lists the top 100 genes were selected which had the highest number of human-unique motifs in their promoter/intron. Listed in tab “top genes (based on promoters)” are genes which were found in at least three top 100 lists. This was done separately for core, proximal, and distal promoters, and also for introns in the tab “top genes (based on introns)”. Fifty gene variants (38 genes) were found which both in the proximal and distal promoter sets appeared. One hundred four genes (their NP id, GeneCard name and annotation) were found which were listed in at least 3 top 100 gene lists whose introns contained statistically significant human-unique intron motifs. (XLSX 5181 kb)