Synthesis of 2,3,4,11b-Tetrahydro-1H-pyridazino[6,1-a]isoquinolines via the Three-Component Reaction of 2-Alkynylbenzaldehydes, a Sulfonohydrazide and Dimethyl Cyclopropane-1,1-dicarboxylate
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下载链接：
http://www.thieme-connect.com/DOI/DOI?10.1055/s-0030-1260063
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资源简介：
A three-component reaction of 2-alkynylbenzaldehydes, a sulfonohydrazide
and dimethyl cyclopropane-1,1-dicarboxylate, co-catalyzed by silver(I)
triflate and nickel(II) perchlorate hexahydrate, is described, which
affords 2,3,4,11b-tetrahydro-1H-pyridazino[6,1-a]isoquinolines in moderate
to good yields. A possible reaction pathway that proceeds via a
tandem 6-endo-cyclization and [3+3] cycloaddition
sequence is proposed.
提供机构：
Georg Thieme Verlag, Stuttgart, New York
创建时间：
2011-11-30
