Evolution of robustness to protein mistranslation by accelerated protein turnover

To investigate how organisms mitigate the deleterious effects of mistranslation during evolution, a mutant tRNA was expressed in S. cerevisiae为探究生物体在进化历程中如何缓解错译所引发的有害效应，研究人员在酿酒酵母（Saccharomyces cerevisiae，缩写S. cerevisiae）中表达了突变型转运RNA（transfer RNA，tRNA）。