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Mechanism of inert inflammation in an immune checkpoint blockade-resistant tumor subtype bearing transcription elongation defects

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NIAID Data Ecosystem2026-03-13 收录
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High baseline CTLs in TEdef+ tumors result from the aberrant activation of the Nucleic Acid Sensing-TBK1-CCL5/CXCL9 signaling cascade, which induces an immunosuppressive microenvironment with increased regulatory T cells and exhausted CTLs. 2 Control, 2 Flavopiridol teated

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2022-09-06
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