The Prins Reaction Using Ketones: Rationalization and Application toward the Synthesis of the Portentol Skeleton
收藏NIAID Data Ecosystem2026-03-07 收录
下载链接：
https://figshare.com/articles/dataset/The_Prins_Reaction_Using_Ketones_Rationalization_and_Application_toward_the_Synthesis_of_the_Portentol_Skeleton/2565382
下载链接
链接失效反馈官方服务：
资源简介：
We report a TMSI-promoted Prins cyclization reaction with ketones as carbonyl partners to prepare polysubstituted chiral spirotetrahydropyrans. In the presence of racemic 2-methylcyclohexanone a dynamic kinetic resolution occurred affording one stereoisomer. The observed enantiospecificity has been rationalized by DFT calculation.
创建时间：
2016-02-22
