NAT10-mediated ac4C modification promotes neuroectoderm specification of human embryonic stem cells via acetylating NR2F1 mRNA to enhance translation efficiency [Ribo-seq]

We use Ribo-seq to report the most comprehensive survey to date of mRNA translation in human embryonic stem cells (hESCs), neuroepithelial progenitors cells(NEP) and mesendoderm cells(ME) Overall design: the mRNA translation profile of human embryonic stem cells (hESCs), neuroepithelial progenitors cells(NEP) and mesendoderm cells(ME)