NEW EMBO MEMBERS’ REVIEW
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NEW EMBO MEMBERS’ REVIEW
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2001-03-01
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Glucocorticoids inhibit MAP kinase via increased expression and decreased degradation of MKP-1
Glucocorticoids inhibit the proinflammatory activities of transcription factors such as AP-1 and NF-κB as well as that of diverse cellular signaling molecules. One of these signaling molecules is the
PubMed Central2001-12-17 更新30
The structure of an AspRS–tRNA(Asp) complex reveals a tRNA-dependent control mechanism
The 2.6 Å resolution crystal structure of an inactive complex between yeast tRNA(Asp) and Escherichia coli aspartyl-tRNA synthetase reveals the molecular details of a tRNA-induced mechanism that contr
PubMed Central2001-09-17 更新30
DNA polymerase β is the major dRP lyase involved in repair of oxidative base lesions in DNA by mammalian cell extracts
The repair of oxidative base lesions in DNA is a coordinated chain of reactions that includes removal of the damaged base, incision of the phosphodiester backbone at the abasic sugar residue, incorpor
PubMed Central2001-12-03 更新10
Structural basis for the interaction between NTF2 and nucleoporin FxFG repeats
Interactions with nucleoporins containing FxFG-repeat cores are crucial for the nuclear import of RanGDP mediated by nuclear transport factor 2 (NTF2). We describe here the 1.9 Å resolution crystal st
PubMed Central2002-06-17 更新30
Two isoforms of Serpent containing either one or two GATA zinc fingers have different roles in Drosophila haematopoiesis
serpent (srp) encodes a GATA transcription factor essential for haematopoiesis in Drosophila. Previously, Srp was shown to contain a single GATA zinc finger of C-terminal type. Here we show that srp e
PubMed Central2002-10-15 更新20



