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Synthesis of Selenyl-Substituted Quinoline Derivatives via Substrate-Controlled Three-Component Domino Reactions

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NIAID Data Ecosystem2026-03-14 收录
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A simple and efficient method for the preparation of selenyl-substituted quinoline derivatives through a CSp3–H selenylation of in situ-generated 3-acetyl quinoline has been developed. This protocol is easy to handle, scalable, and good functional group tolerant, providing a rapid method to 3-selenoacetyl quinoline and 3-diselenoacetyl quinoline derivatives.

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2022-09-16
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