Genome-wide analysis of liver gene expression in prenatally undernourished male rat offspring under high-fat diet

Based on the developmental origin of health of disease hypothesis, we previously showed that prenatal 70% maternal food restriction (FR30) predisposes the offspring to development of pathologies in adulthood. In the present study, we focused on the liver gene expression profile of standard and high fat (HF)-fed FR30 adult offspring.基于健康与疾病的发育起源（developmental origin of health of disease）假说，我们此前的研究已证实，母体孕期70%食物限制（FR30）会使子代在成年后易罹患各类病理病症。本研究聚焦于正常膳食与高脂（HF）喂养的FR30成年子代的肝脏基因表达谱。