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Crystal structure of human TLR8 in complex with Compound 15

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Protein Data Bank Japan2024-11-13 更新2026-04-19 收录
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Crystal structure of human TLR8 in complex with Compound 15 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 5-cyclopropyl-6-(2,6-dimethylpyridin-4-yl)-~{N}-[(3~{R},4~{R})-3-fluoranylpiperidin-4-yl]-1~{H}-indazol-3-amine, Toll-like receptor 8, ... Authors: Faller, M, Zink, F. Deposit date: 2022-02-10 Release date: 2022-03-23 Last modified: 2024-11-13 Method: X-RAY DIFFRACTION (3.121 Å) Cite: Structure-Based Optimization of a Fragment-like TLR8 Binding Screening Hit to an In Vivo Efficacious TLR7/8 Antagonist. Acs Med.Chem.Lett., 13, 2022
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2022-02-10
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