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Expression and function of PML-RARA in the multipotent hematopoietic progenitor cells of Ctsg-PML-RARA mice

ChEBI2012-08-13 更新2026-07-21 收录

急性早幼粒细胞白血病机制

造血祖细胞

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-40022 数据链接链接失效反馈

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资源简介：

Expression and function of PML-RARA in the multipotent hematopoietic progenitor cells of Ctsg-PML-RARA mice

应用场景：

创建时间：

2012-08-13

单细胞分析

造血祖细胞

Granulocyte-monocyte progenitors (GMPs) have been previously defined for their potential to generate various myeloid progenies such as neutrophils and monocytes. Although studies have proposed lineage

NIAID Data Ecosystem110

Competing dynamic gene regulatory networks involved in fibroblast reprogramming to haematopoietic progenitor cells [scRNA-Seq]

细胞重编程

造血祖细胞

Direct reprogramming of somatic cells offers a potentially safer therapeutic approach to generate patient-specific haematopoietic cells. However, this strategy is limited by stochasticity of reprogram

NIAID Data Ecosystem30

UM171 expands distinct types of myeloid and lymphoid progenitors from human pluripotent stem cells.. UM171 expands distinct types of myeloid and lymphoid progenitors from human pluripotent stem cells.

造血祖细胞

基因表达谱分析

Overall, our studies revealed that UM171 differentially enriches specific populations of hematopoietic progenitors, in HSC expansion and lymphoid culture conditions, and that it is a potent small mole

NIAID Data Ecosystem20

Expression and Function of PML-RARA in the Hematopoietic Progenitor Cells of Ctsg-PML-RARA Mice

急性早幼粒细胞白血病机制

造血干细胞功能

Because PML-RARA-induced acute promyelocytic leukemia (APL) is a morphologically differentiated leukemia, many groups have speculated about whether its leukemic cell of origin is a committed myeloid p

NIAID Data Ecosystem60

An immunophenotype coupled transcriptomic atlas of human hematopoietic progenitors

造血祖细胞

免疫表型与转录组整合

Understanding the cellular heterogeneity and lineage potential of human bone marrow hematopoietic progenitors is required to understand normal differentiation and the mechanisms of hematological disea

NIAID Data Ecosystem20

Expression and function of PML-RARA in the multipotent hematopoietic progenitor cells of Ctsg-PML-RARA mice

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