The FK1 domain of FKBP51 in complex with the macrocyclic SAFit analog p5(1,1)-(E)
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The FK1 domain of FKBP51 in complex with the macrocyclic SAFit analog p5(1,1)-(E) Descriptor: (2~{S},9~{S},13~{E})-2-cyclohexyl-18,21-dimethoxy-11,16-dioxa-4-azatricyclo[15.2.2.0^{4,9}]henicosa-1(19),13,17,20-tetraene-3,10-dione, Peptidyl-prolyl cis-trans isomerase FKBP5 Authors: Meyners, C, Spiske, M, Hausch, F. Deposit date: 2024-09-09 Release date: 2025-01-15 Last modified: 2025-03-19 Method: X-RAY DIFFRACTION (2.301 Å) Cite: Conformationally Restricted Macrocycles as Improved FKBP51 Inhibitors Enabled by Systematic Linker Derivatization. Angew.Chem.Int.Ed.Engl., 64, 2025
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2024-09-09
