Supplementary Material for "Updating and Extending an UV/Vis Spectroscopy-Based Assay for Monitoring of Transformations Between Nucleosides and Nucleobases"

This is the supplementary material for our publication "Updating and Extending an UV/Vis Spectroscopy-Based Assay for Monitoring of Transformations Between Nucleosides and Nucleobases".

For a detailed description of this material, please see the "Notes on the Supporting Material".

Naturally, this publication builds on previous work. The Python code used for spectral unmixing is available on this platform (10.5281/zenodo.3243376) and has been described in our previous publication (10.3390/mps2030060, 10.5281/zenodo.3333469). Applications of this methodology are described in our recent article in Adv. Synth. Catal. (10.1002/adsc.201901230) and its supporting material (10.5281/zenodo.3568858).

I wish to thank all authors of this publication for their contribution, using the method and generously sharing your experience and your data with me. This helped us develop robust protocols, learn about the potential and limits of the method and ultimately made this update article possible. While I have been the primary user of the method, your applications, questions and problems have spurred us to think outside of the box and find solutions that helped us expand our repertoire of "unmixable" reactions. This Supplementary Information contains some of our shared data and I thank each of you for contributing to this work.