Direct DNA crosslinking with CAP-C uncovers transcription-dependent chromatin organization at high resolution

Name: Direct DNA crosslinking with CAP-C uncovers transcription-dependent chromatin organization at high resolution
Creator: University of Connecticut Health Center
Published: 2022-02-20T00:00:00+08:00

干细胞与再生医学数据中心2022-02-20 更新2024-03-06 收录

染色质结构

生物技术

数据链接：

http://data.iscr.ac.cn/Article?id=38b585199548f48dc832ed36c77c458c 数据链接链接失效反馈

官方服务：

资源简介：

We introduce Chemical-crosslinking Assisted Proximity Capture (CAP-C), a method that utilizes multi-functional chemical crosslinkers with defined physical sizes to directly assess spatial distances between nuclear genomic sequences. CAP-C avoids limitations caused by extensive protein-DNA crosslinking in most in situ methods, and thus generates chromatin contact maps at high resolution with low background noise.

提供机构：

University of Connecticut Health Center

创建时间：

2022-02-20