An Open Dataset for Combined Aerobic Exercise and Video Game Intervention in Older Adults

Mnemonic discrimination is very vulnerable to aging. Previous studies have reported that aerobic exercise and enriched cognitive stimulation (e.g., video games) could improve mnemonic discrimination in older adults. The animal model suggested that combining the 2 training methods could result in a larger improvement. However, there is limited evidence on the potential superior efficacy of combined intervention with human participants. Moreover, the neural basis of this potential superior is poorly understood.In the present dataset, we conducted a 16-week intervention trial with 98 community-dwelling older adults assigned to one of the four groups (combined training, aerobic cycling alone, video game alone, or passive control). The image data was obtained using a 3 Tesla GE Discovery MR750 Magnetic Resonance Scanner with 8-channel head-coils.