Data underlying the publication: Heterogeneity and genomic plasticity of clinical isolates of Acinetobacter baumannii and Acinetobacter nosocomialis from India

This dataset encompasses raw data and statistical inferences from a comprehensive study focused on understanding the growth dynamics, biofilm formation capabilities, synergistic antimicrobial susceptibilities, and time-kill kinetics of various strains of <em>Acinetobacter </em>species. The objective of this research was to elucidate the pathogenic characteristics and to evaluate the in vitro efficacy of antibiotic combinations in demonstrating synergy. Employing a mixed-methods approach, the data was collected through laboratory-based experimental procedures, including growth curve assays to monitor bacterial proliferation, biofilm formation assays to assess the capacity to form biofilms, checkerboard assays for determining the synergy between different antimicrobials, and time-kill kinetics experiments to evaluate the effectiveness of antibiotics over time. The dataset contains quantitative measurements facilitating a comprehensive analysis of the pathogenic behaviour of <em>Acinetobacter</em> species and their interactions with antimicrobial agents.

本数据集涵盖了一项针对不动杆菌属（Acinetobacter）各菌株的生长动态、生物膜形成能力、协同抗菌敏感性及杀菌时间动力学特性的综合性研究的原始数据与统计推断结果。本研究的目标为阐明该菌的致病特征，并评估抗生素联合用药的体外协同抗菌效果。本研究采用混合研究方法，通过一系列实验室实验流程采集数据，包括用于监测细菌增殖的生长曲线测定实验、用于评估菌株形成生物膜能力的生物膜形成实验、用于确定不同抗菌药物间协同作用的棋盘格法实验，以及用于评估抗生素随时间推移的抗菌效果的时间杀菌动力学实验。本数据集包含定量测量数据，可用于全面分析不动杆菌属菌株的致病行为及其与抗菌药物的相互作用。