Transcriptomic profile of the hippocampus of rat strains with contrasting nervous system excitability

Bulk RNA sequencing of the hippocampus in male rats from two selectively bred strains differing in nervous system excitability: LT (low threshold, high-excitability) and HT (high threshold, low-excitability). The aim was to characterize baseline interstrain transcriptomic divergence in intact animals and identify major functional themes associated with inherited differences in excitability.